Association of Left Atrial Size With Stroke or Systemic Embolism in Patients With Atrial Fibrillation Having Undergone Bioprosthetic Valve Replacement From the BPV-AF Registry
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- Tanaka Hidekazu
- Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
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- Takegami Misa
- Department of Preventive Medicine and Epidemiology, National Cerebral and Cardiovascular Center
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- Miyake Makoto
- Department of Cardiology, Tenri Hospital
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- Amano Masashi
- Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
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- Kitai Takeshi
- Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital
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- Fujita Tomoyuki
- Cardiovascular Surgery Department, National Cerebral and Cardiovascular Center
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- Koyama Tadaaki
- Department of Cardiovascular Surgery, Kobe City Medical Center General Hospital
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- Ando Kenji
- Department of Cardiology, Kokura Memorial Hospital
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- Komiya Tatsuhiko
- Department of Cardiovascular Surgery, Kurashiki Central Hospital
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- Izumo Masaki
- Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine
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- Kawai Hiroya
- Department of Cardiology, Hyogo Prefectural Harima-Himeji General Medical Center
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- Eishi Kiyoyuki
- Department of Cardiovascular Surgery, Nagasaki University Hospital
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- Yoshida Kiyoshi
- Department of Cardiology, The Sakakibara Heart Institute of Okayama
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- Kimura Takeshi
- Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University
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- Nawada Ryuzo
- Department of Cardiology, Shizuoka City Shizuoka Hospital
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- Sakamoto Tomohiro
- Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center
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- Shibata Yoshisato
- Department of Cardiology, Miyazaki Medical Association Hospital Cardiovascular Center
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- Fukui Toshihiro
- Department of Cardiovascular Surgery, Graduate School of Medical Sciences, Kumamoto University
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- Minatoya Kenji
- Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University
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- Tsujita Kenichi
- Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
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- Sakata Yasushi
- Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine
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- Kimura Tetsuya
- Primary Medical Science Department, Daiichi Sankyo Co., Ltd.
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- Nishimura Kunihiro
- Department of Preventive Medicine and Epidemiology, National Cerebral and Cardiovascular Center
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- Furukawa Yutaka
- Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital
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- Izumi Chisato
- Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
抄録
<p>Background: The left atrial volume index (LAVI) is important for predicting thromboembolism in patients with non-valvular atrial fibrillation (AF), but the utility of LAVI for predicting thromboembolism in patients with both bioprosthetic valve replacement and AF remains unclear.</p><p>Methods and Results: Of 894 patients from a previous multicenter prospective observational registry (BPV-AF Registry), 533 whose LAVI data had been obtained by transthoracic echocardiography were included in this subanalysis. Patients were divided into tertiles (T1–T3) according to LAVI as follows: T1 (n=177), LAVI=21.5–55.3 mL/m2; T2 (n=178), LAVI=55.6–82.1 mL/m2; T3 (n=178), LAVI=82.5–408.0 mL/m2. The primary outcome was defined as either stroke or systemic embolism for a mean (±SD) follow-up period of 15.3±4.2 months. Kaplan-Meier curves indicated that the primary outcome tended to occur more frequently in the group with the larger LAVI (log-rank P=0.098). Comparison of T1 with T2 plus T3 using Kaplan-Meier curves indicated that patients in T1 experienced significantly fewer primary outcomes (log-rank P=0.028). Furthermore, univariate Cox proportional hazard regression showed that 1.3- and 3.3-fold more primary outcomes occurred in T2 and T3, respectively, than in T1.</p><p>Conclusions: Larger LAVI was associated with stroke or systemic embolism in patients who had undergone bioprosthetic valve replacement and with a definitive diagnosis of AF.</p>
収録刊行物
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- Circulation Reports
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Circulation Reports 5 (5), 210-216, 2023-05-10
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390858994366718848
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- ISSN
- 24340790
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
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- 抄録ライセンスフラグ
- 使用不可