A case of gallbladder sarcoma with differentiation to neuroendocrine carcinoma in metastatic lymph nodes

DOI
  • Nagata Yuki
    Department of Gastroenterological Surgery, Kagoshima City Hospital
  • Maemura Kosei
    Department of Gastroenterological Surgery, Kagoshima City Hospital
  • Yamao Kohei
    Department of Gastroenterological Surgery, Kagoshima City Hospital
  • Ino Satoshi
    Department of Gastroenterological Surgery, Kagoshima City Hospital
  • Hamada Nobuo
    Department of Gastroenterological Surgery, Kagoshima City Hospital
  • Sueyoshi Kazunori
    Department of Pathology, Kagoshima City Hospital

Bibliographic Information

Other Title
  • 転移リンパ節に神経内分泌癌への分化を伴った胆嚢癌肉腫の1切除例

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Abstract

<p>The patient was a 77-year-old female who presented with a mass measuring 90mm long diameter close to the pancreatic head, which was identified incidentally on CT. Based on an EUS-FNA histological examination, the patient was diagnosed with duodenal neuroendocrine carcinoma (NEC), and subtotal stomach-preserving pancreatoduodenectomy was performed. The histopathological assessment showed some lymphatic tissue remaining in the mass, so lymph node metastasis was suspected. The mass consisted mainly of NEC components, and also had adenocarcinomatous and chondrosarcomatous components. The excised specimen showed a nodular lesion was found in the fundus of the gallbladder, and histopathologically it was composed of adenocarcinomatous and chondrosarcomatous components. Metastasis was also found in No.12c lymph node, with only NEC components present. Based on these findings, a diagnosis of gallbladder sarcoma with differentiation to NEC during lymph node metastasis was made. We report this case because it presents an interesting metastatic form and is considered to be a valuable case in terms of tumorigenesis.</p>

Journal

  • Tando

    Tando 37 (2), 246-251, 2023-05-31

    Japan Biliary Association

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