Association Between Serum LDL-cholesterol Levels and Physical Characteristics and Lifestyles Among Male Medical Examinees

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  • 人間ドック男性受診者における血清LDLコレステロール値と身体特性・生活習慣の関連
  • ニンゲン ドック ダンセイ ジュシンシャ ニ オケル ケッセイ LDL コレステロールチ ト シンタイ トクセイ ・ セイカツ シュウカン ノ カンレン

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Abstract

<p>Objective: We investigated the factors for improving serum LDL-cholesterol (s-LDL-C) levels from the perspective of physical characteristics and lifestyles of male medical examinees. </p><p>Subjects and Methods: Subjects were the 340 male medical examinees of our medical clinic during the same period in 2017 and 2018. We classified them into four groups (maintained, improved, worsened and non-improved) based on the change in s-LDL-C levels. χ2 tests were conducted to compare factors among the four groups and pairwise comparisons with Bonferroni adjustment were conducted for each statistically significant factor. Logistic regression analysis was also performed to examine the association between s-LDL-C levels and each factor. </p><p>Results: There were significant differences among the four groups in BMI, body fat percentage, fatty liver, long-term weight gain, physical activities and snacking between meals. The non-improved group had higher proportions of BMI above 25 kg/m2 (obesity), body fat percentage over 25%, fatty liver and long-term weight gain than the maintained group. The maintained and improved groups had a higher proportion of physical activities than the non-improved group. The worsened group was more likely to snack between meals than the maintained and non-improved groups. In logistic regression analysis stratified by s-LDL-C level in the previous year, snacking between meals showed a negative association with improved s-LDL-C levels in the <140 mg/dL group, and non-obesity and physical activities showed positive associations in the ≥140 mg/dL group. </p><p>Conclusion: Examinees who snacked between meals increased their levels to ≥140 mg/dL, while those who were not obese or who engaged in physical activity decreased their s-LDL-C levels to <140 mg/dL.</p>

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