Effect of Temporal Sampling Rate on Estimates of the Perfusion Parameters for Patients with Moyamoya Disease Assessed with Simultaneous Multislice Dynamic Susceptibility Contrast-enhanced MR Imaging
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- Takamura Tomohiro
- Department of Radiology, Shizuoka General Hospital Department of Radiology, Juntendo University
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- Hara Shoko
- Department of Neurosurgery, Tokyo Medical and Dental University
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- Nariai Tadashi
- Department of Neurosurgery, Tokyo Medical and Dental University
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- Ikenouchi Yutaka
- Department of Radiology, Juntendo University
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- Suzuki Michimasa
- Department of Radiology, Juntendo University
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- Taoka Toshiaki
- Department of Radiology, Nagoya University
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- Ida Masahiro
- Department of Radiology, Mito Medical Center
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- Ishigame Keiichi
- Department of Radiology, Kenshinkai Tokyo Medical Clinic
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- Hori Masaaki
- Department of Radiology, Juntendo University Department of Radiology, Toho University Omori Medical Center
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- Sato Kanako
- Department of Radiology, Juntendo University
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- Kamagata Koji
- Department of Radiology, Juntendo University
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- Kumamaru Kanako
- Department of Radiology, Juntendo University
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- Oishi Hidenori
- Department of Neurosurgery, Juntendo University
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- Okamoto Sho
- Department of Neurosurgery, Nagoya University
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- Araki Yoshio
- Department of Neurosurgery, Nagoya University
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- Uda Kenji
- Department of Neurosurgery, Nagoya University
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- Miyajima Masakazu
- Department of Neurosurgery, Juntendo Tokyo Koto Geriatric Medical Center
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- Maehara Taketoshi
- Department of Neurosurgery, Tokyo Medical and Dental University
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- Inaji Motoki
- Department of Neurosurgery, Tokyo Medical and Dental University
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- Tanaka Yoji
- Department of Neurosurgery, Tokyo Medical and Dental University
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- Naganawa Shinji
- Department of Radiology, Nagoya University
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- Kawai Hisashi
- Department of Radiology, Nagoya University
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- Nakane Toshiki
- Department of Radiology, Nagoya University
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- Tsurushima Yasuaki
- Department of Radiology, Kenshinkai Tokyo Medical Clinic
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- Onodera Toshiyuki
- Department of Radiology, Tokyo Metropolitan Cancer Detection Center
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- Nojiri Shuko
- Clinical Research and Trial Center, Juntendo Hospital
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- Aoki Shigeki
- Department of Radiology, Juntendo University
抄録
<p>Purpose: The effect of temporal sampling rate (TSR) on perfusion parameters has not been fully investigated in Moyamoya disease (MMD); therefore, this study evaluated the influence of different TSRs on perfusion parameters quantitatively and qualitatively by applying simultaneous multi-slice (SMS) dynamic susceptibility contrast-enhanced MR imaging (DSC-MRI).</p><p>Methods: DSC-MRI datasets were acquired from 28 patients with MMD with a TSR of 0.5 s. Cerebral blood flow (CBF), cerebral blood volume (CBV), mean transit time (MTT), time to peak (TTP), and time to maximum tissue residue function (Tmax) were calculated for eight TSRs ranging from 0.5 to 4.0 s in 0.5-s increments that were subsampled from a TSR of 0.5 s datasets. Perfusion measurements and volume for chronic ischemic (Tmax ≥ 2 s) and non-ischemic (Tmax < 2 s) areas for each TSR were compared to measurements with a TSR of 0.5 s, as was visual perfusion map analysis.</p><p>Results: CBF, CBV, and Tmax values tended to be underestimated, whereas MTT and TTP values were less influenced, with a longer TSR. Although Tmax values were overestimated in the TSR of 1.0 s in non-ischemic areas, differences in perfusion measurements between the TSRs of 0.5 and 1.0 s were generally minimal. The volumes of the chronic ischemic areas with a TSR ≥ 3.0 s were significantly underestimated. In CBF and CBV maps, no significant deterioration was noted in image quality up to 3.0 and 2.5 s, respectively. The image quality of MTT, TTP, and Tmax maps for the TSR of 1.0 s was similar to that for the TSR of 0.5 s but was significantly deteriorated for the TSRs of ≥ 1.5 s.</p><p>Conclusion: In the assessment of MMD by SMS DSC-MRI, application of TSRs of ≥ 1.5 s may lead to deterioration of the perfusion measurements; however, that was less influenced in TSRs of ≤ 1.0 s.</p>
収録刊行物
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- Magnetic Resonance in Medical Sciences
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Magnetic Resonance in Medical Sciences 22 (3), 301-312, 2023
日本磁気共鳴医学会