Antifungal effect of <i>Moringa oleifera</i> leaf extract on <i>Candida albicans</i>
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- YOSHIMATSU Hideki
- Department of Preventive and Community Dentistry, Osaka Dental University
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- TANAKA Reiji
- Fourth year student, School of Dentistry, Osaka Dental University
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- KAWAMURA Kahori
- Department of Preventive and Community Dentistry, Osaka Dental University
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- HUANG Zheqi
- Department of Preventive and Community Dentistry, Osaka Dental University Graduate School of Dentistry (Department of Preventive and Community Dentistry), Osaka Dental University
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- KAMADA Sayuri
- Department of Preventive and Community Dentistry, Osaka Dental University Graduate School of Dentistry (Department of Preventive and Community Dentistry), Osaka Dental University
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- FUKUHARA Takahisa
- Department of Preventive and Community Dentistry, Osaka Dental University
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- KANO Keita
- Department of Preventive and Community Dentistry, Osaka Dental University
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- DOI Takashi
- Department of Preventive and Community Dentistry, Osaka Dental University
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- MIYAKE Tatsuro
- Department of Preventive and Community Dentistry, Osaka Dental University
説明
<p>Candida albicans is a common pathogen, especially in immunocompromised patients. What is concerning is that this pathogen is displaying increasing resistance to azole drugs, which are commonly used to treat it. We investigated the antifungal activity of Moringa oleifera leaves against C. albicans. The fungicidal effect of C. albicans exposed to Moringa oleifera leaves was determined using adenosine triphosphate (ATP) bioluminescence. Moringa oleifera leaves showed antifungal activity against C. albicans with a minimum inhibitory concentration (MIC) of 50 μg/mL. Additionally, at the MIC, the Moringa oleifera leaves significantly reduced ATP-leakage. This study provides sufficient evidence of the in vitro antifungal effects of Moringa oleifera leaves against C. albicans. (J Osaka Dent Univ 2023; 57: 295-299)</p>
収録刊行物
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- Journal of Osaka Dental University
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Journal of Osaka Dental University 57 (2), 295-299, 2023-10-25
大阪歯科学会
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詳細情報 詳細情報について
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- CRID
- 1390860852414660736
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- ISSN
- 21896488
- 04752058
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- 本文言語コード
- en
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- データソース種別
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- JaLC
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- 抄録ライセンスフラグ
- 使用不可