Expectations and Challenges for RNA-Targeted Small Molecule Drug Discovery

DOI

Bibliographic Information

Other Title
  • RNA標的低分子創薬への期待と課題

Abstract

Small molecule drug discovery research targeting RNA is accelerating. Although academia has long suggested that RNA is a potential drug discovery target, the proposal has been neglected in our country. In my laboratory, our goal has been to present as many facts as possible that “small molecules that bind to nucleic acids can be involved in the regulation of functional expression in vivo” so that not only the academic world but also the industrial world can realize the potential of the combination of small molecules and nucleic acids. In the following, I would like to introduce my research to date, and give my opinion on the challenges of RNA-targeted small molecule drug discovery, which is now attracting the attention of many people.

Journal

  • MEDCHEM NEWS

    MEDCHEM NEWS 33 (4), 158-164, 2023-11-01

    The Pharmaceutical Society of Japan

Keywords

Details 詳細情報について

  • CRID
    1390860929792130048
  • DOI
    10.14894/medchem.33.4_158
  • ISSN
    24328626
    24328618
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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