A case of thyroid-like low-grade nasopharyngeal papillary adenocarcinoma of the posterior end of the nasal septum

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  • Kamimura Seiichiro
    Department of Otolaryngology-Head and Neck Surgery. Tokushima University, Institute of Biomedical Sciences, Tokushima University Graduate School
  • Ishitani Yuki
    Department of Otolaryngology-Head and Neck Surgery. Tokushima University, Institute of Biomedical Sciences, Tokushima University Graduate School
  • Ishitani Keisuke
    Department of Otolaryngology-Head and Neck Surgery. Tokushima University, Institute of Biomedical Sciences, Tokushima University Graduate School
  • Tomura Miki
    Department of Otolaryngology-Head and Neck Surgery. Tokushima University, Institute of Biomedical Sciences, Tokushima University Graduate School
  • Endo Aki
    Department of Otolaryngology-Head and Neck Surgery. Tokushima University, Institute of Biomedical Sciences, Tokushima University Graduate School
  • Kanamura Ryo
    Department of Otolaryngology-Head and Neck Surgery. Tokushima University, Institute of Biomedical Sciences, Tokushima University Graduate School
  • Shono Hitoshi
    Department of Otolaryngology-Head and Neck Surgery. Tokushima University, Institute of Biomedical Sciences, Tokushima University Graduate School
  • Kondo Eiji
    Department of Otolaryngology-Head and Neck Surgery. Tokushima University, Institute of Biomedical Sciences, Tokushima University Graduate School
  • Azuma Takahiro
    Department of Otolaryngology-Head and Neck Surgery. Tokushima University, Institute of Biomedical Sciences, Tokushima University Graduate School
  • Sato Go
    Department of Otolaryngology-Head and Neck Surgery. Tokushima University, Institute of Biomedical Sciences, Tokushima University Graduate School
  • Kitamura Yoshiaki
    Department of Otolaryngology-Head and Neck Surgery. Tokushima University, Institute of Biomedical Sciences, Tokushima University Graduate School

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  • 鼻中隔後端に生じたThyroid-like low-grade nasopharyngeal papillary adenocarcinoma例

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Thyroid-like low-grade nasopharyngeal papillary adenocarcinoma （TL-LGNPPA） is a rare low-grade tumor that predominantly occurs in the nasopharynx. The tumor shows papillary thyroid carcinoma-like histopathology, positive for thyroid transcription factor-1 （TTF-1）, but negative for thyroglobulin. We report a case of TL-LGNPPA at the posterior end of the nasal septum. A 30-year-old woman was found by chance to have a tumor at the posterior end of the nasal septum. We preoperatively diagnosed the tumor as an exophytic papilloma and endoscopically resected the tumor. The tumor was diagnosed by postoperative histopathology as TL-LGNPPA. More than one year after surgery, there is no evidence of recurrence or metastasis.

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