A MULTICENTER CLINICAL SURVEY ABOUT THE PREVALENCE OF JAPANESE CYPRESS POLLINOSIS AND THE EFFICACY OF SUBLINGUAL IMMUNOTHERAPY WITH JAPANESE CEDAR POLLEN EXTRACT DURING JAPANESE CYPRESS POLLEN DISPERSAL PERIOD
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- Oka Aiko
- Department of Otorhinolaryngology, Head and Neck Surgery, International University of Health and Welfare Narita Hospital
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- Yuta Atsushi
- Yuta Clinic
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- Okawa Yukiko
- Yuta Clinic
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- Masuno Satoru
- Mikinohara ENT Clinic
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- Tsunoda Takatsugu
- Hidamari Clinic
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- Takahara Eriko
- Chofu Ekimae ENT Clinic
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- Terada Akihiko
- Terada Allergy Kodomo Clinic
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- Kanai Kenichi
- Kosugi ENT Clinic
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- Nagakura Hitoshi
- Nagakura ENT Allergy Clinic
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- Mimura Hideya
- Mimura Clinic
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- Arao Harumi
- Arao Internal Medicine and Otolaryngology Clinic
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- Ueyama Shigehiro
- Funai Clinic
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- Ueyama Akiyo
- Funai Clinic
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- Tokuda Reiko
- Tokuda Family Clinic
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- Bamba Hitoshi
- BAMBA ENT Clinic
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- Nakazato Hidehisa
- Oyamanakamaru Clinic
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- Nakazato Mahoko
- Oyamanakamaru Clinic
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- Amesara Ryo
- Amesara ENT Clinic
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- Nakai Shigeru
- Nakai ENT Clinic
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- Araki Susumu
- Otaka no Mori ENT Morning Clinic
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- Sakaida Mayuko
- Mie E.N.T. Clinic
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- Tokuriki Masaharu
- Tokuriki ENT Clinic
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- Hama Takemitsu
- Hama ENT Clinic
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- Chiba Mayumi
- Chiba Dermatology and Otolaryngology Clinic
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- Ikeda Hiroki
- Ikeda ENT Clinic
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- Togawa Akihisa
- Sansan Clinic
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- Tsuzuki Hideaki
- Miyako Ear, Nose and Throat Clinic
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- Hyo Yukiyoshi
- Hyo ENT Clinic
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- Niitsu Sumiko
- Niitsu Clinic
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- Ohkawa Chikahisa
- Okawa ENT Clinic
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- Nakamoto Setsuo
- Nakamoto Ear Nose Throat Clinic
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- Takeo Tetsu
- Takeo ENT Clinic
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- Kumanomidou Hiroshi
- Kumanomidou ENT Clinic
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- Kanai Kengo
- Department of Otorhinolaryngology, Head and Neck Surgery, International University of Health and Welfare Narita Hospital
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- Kitamura Hiroshi
- Department of Otorhinolaryngology, Head and Neck Surgery, International University of Health and Welfare Narita Hospital
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- Sugiura Ruka
- International University of Health and Welfare, School of Medicine
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- Okano Mitsuhiro
- Department of Otorhinolaryngology, Head and Neck Surgery, International University of Health and Welfare Narita Hospital
Bibliographic Information
- Other Title
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- スギ花粉舌下免疫療法患者におけるヒノキ花粉症とヒノキ花粉飛散期効果に関する多機関実態調査
- スギ カフン ゼッカ メンエキ リョウホウ カンジャ ニ オケル ヒノキ カフンショウ ト ヒノキ カフン ヒサンキ コウカ ニ カンスル タキカン ジッタイ チョウサ
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Abstract
<p>Background: Little is known whether sublingual immunotherapy using Japanese cedar pollen extract (cedar SLIT) is effective for not only Japanese cedar pollinosis but also Japanese cypress pollinosis. We investigated the prevalence rate of Japanese cypress pollinosis, efficacy of cedar SLIT on cypress pollinosis and patients' wish to receive cypress SLIT.</p><p>Methods: We investigated a multi-center (31 institutions), cross-sectional survey using a self-administrated questionnaire with four questions for patients received cedar SLIT aged from 5 to 69 years old.</p><p>Results: 2523 subjects were enrolled for analysis. 83.4% of them had pollinosis symptoms during cypress season before cedar SLIT. In such patients, 37.4% experienced lessened efficacy of cedar SLIT during cypress season. Both the prevalence of cypress pollinosis and the lessened efficacy of cedar SLIT on cypress pollinosis were significantly seen in western Japan as compared to eastern Japan. 76.1% of the subject having cypress pollinosis before SLIT wished to receive cypress SLIT if it is available.</p><p>Conclusion: A lessened efficacy of cedar SLIT during cypress season was broadly seen in Japan, and further showed a regional difference. Together with the finding of high wish by patients, these results suggest a development of cypress SLIT is desirable.</p>
Journal
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- Japanese Journal of Allergology
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Japanese Journal of Allergology 72 (9), 1138-1146, 2023
Japanese Society of Allergology
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Keywords
Details 詳細情報について
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- CRID
- 1390861074218820864
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- NII Book ID
- AN00012583
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- ISSN
- 13477935
- 00214884
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- NDL BIB ID
- 033165344
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
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- Abstract License Flag
- Disallowed