A Case of Intramural Cystic Lesion of the Gallbladder with Low-grade Atypical Mucinous Epithelium

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  • SUGIU Kumi
    Department of Surgery, Onomichi Municipal HospitalDepartment of Surgery, Okayama Central HospitalDepartment of Pathology & Microbiology, Faculty of Medicine, Saga University Department of Surgery, Onomichi Municipal HospitalDepartment of Surgery, Okayama Central HospitalDepartment of Pathology & Microbiology, Faculty of Medicine, Saga University
  • MURATA Toshihiro
    Department of Surgery, Onomichi Municipal HospitalDepartment of Surgery, Okayama Central HospitalDepartment of Pathology & Microbiology, Faculty of Medicine, Saga University
  • KAWAMATA Osamu
    Department of Surgery, Onomichi Municipal HospitalDepartment of Surgery, Okayama Central HospitalDepartment of Pathology & Microbiology, Faculty of Medicine, Saga University
  • IMADA Takako
    Department of Surgery, Onomichi Municipal HospitalDepartment of Surgery, Okayama Central HospitalDepartment of Pathology & Microbiology, Faculty of Medicine, Saga University
  • MAKABE Mikio
    Department of Surgery, Onomichi Municipal HospitalDepartment of Surgery, Okayama Central HospitalDepartment of Pathology & Microbiology, Faculty of Medicine, Saga University
  • AISHIMA Shinichi
    Department of Surgery, Onomichi Municipal HospitalDepartment of Surgery, Okayama Central HospitalDepartment of Pathology & Microbiology, Faculty of Medicine, Saga University

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Other Title
  • 低異型粘液性上皮を伴う胆囊壁内囊胞性病変の1例
  • テイイケイ ネンエキセイ ジョウヒ オ トモナウ タンノウヘキ ナイノウホウセイ ビョウヘン ノ 1レイ

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<p>A 71-year-old man who had been pointed out having gallstone was diagnosed with cholelithiasis and adenomyomatosis by preoperative abdominal MRI. Laparoscopic cholecystectomy was performed. The resected specimen included a 25-mm submucosal tumor-like ridging that was found to be a multilocular cystic lesion on the section. Histopathology disclosed adenmyomatosis and multilocular cystic lesion due to mucinous epithelium localized in the gallbladder wall. The cystic epithelium was partly positive for MUC5AC and MCU6, that characterized of gastric-type mucus, with a part comprising low-grade atypical epithelium. Our case was of an intramurally growing cystic lesion localized in the gallbladder wall. Morphologically, it is designated as intramural multicystic mucinous neoplasm with low-grade intraepithelial neoplasia. Due to the rarity of pathological features, we here present this case.</p>

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