Efficacy and Safety of a Cryobiopsy for Central Airway Lesions

DOI
  • Murata Daiki
    Division of Respiratory Medicine, Saga-Ken Medical Centre Koseikan
  • Ohno Shuuhei
    Division of Respiratory Medicine, Saga-Ken Medical Centre Koseikan
  • Sadamatsu Hironori
    Division of Respiratory Medicine, Saga-Ken Medical Centre Koseikan
  • Umeguchi Hitomi
    Division of Respiratory Medicine, Saga-Ken Medical Centre Koseikan
  • Kubota Mio
    Division of Respiratory Medicine, Saga-Ken Medical Centre Koseikan
  • Iwanaga Kentaro
    Division of Respiratory Medicine, Saga-Ken Medical Centre Koseikan

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Other Title
  • 中枢気道病変に対するクライオ生検の有効性と安全性に関する検討

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Abstract

<p>Background. A cryobiopsy has been widely used in recent years; however, while there are many reports of peripheral lung lesions, there are few reports of central airway lesions from Japan. Purpose. To evaluate the efficacy and safety of a cryobiopsy for central airway lesions. Methods. We retrospectively reviewed 11 patients who underwent a cryobiopsy for central airway lesions between September 2019 and December 2022 in our hospital. The efficacy was assessed based on the pathological diagnostic yield for central airway lesions, while the safety was assessed based on bleeding and worsening of the respiratory status. Results. The pathological diagnostic yield of a cryobiopsy was 100%. Bleeding was observed in 10 of the 11 patients (90.9%) but was well controlled in all patients. No cases of a worsening respiratory status after a cryobiopsy were noted. Some patients achieved successful recanalization and improved respiratory symptoms. Conclusion. A cryobiopsy for central airway lesions is a safe technique with a good pathological diagnostic yield. Further studies on cryobiopsy for central airway lesions should be performed in Japan.</p>

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