Effectiveness of Sandwich Method with Artificial Dermis: Current Status of Multicenter Prospective Observational Study

DOI
  • Yamamoto Ryo
    Department of Emergency and Critical Care Medicine, Keio University School of Medicine
  • Sato Yukio
    Department of Emergency and Critical Care Medicine, Keio University School of Medicine
  • Matsumura Hajime
    Department of Plastic Surgery, Tokyo Medical University Hospital
  • Ikeda Hiroto
    Aoyagi Hospital
  • Imai Yoshimichi
    Department of Plastic and Reconstructive Surgery, Tohoku University Graduate School of Medicine
  • Ueda Takahiro
    Advanced Emergency & Critical Care Medical Center, Tottori University Hospital
  • Fukuda Norio
    Department of Dentistry, Oral and Maxillofacial Plastic and Reconstructive Surgery, School of Medicine, Faculty of Medicine, Yamagata University
  • Sasaki Junichi
    Department of Emergency and Critical Care Medicine, Keio University School of Medicine

Bibliographic Information

Other Title
  • 人工真皮サンドウィッチ法の有用性：多施設共同前向き観察研究の立案および現状

Abstract

<p> There are various surgical techniques for skin grafts, among which grafting with artificial dermis has been suggested to enhance the skin function and esthetics. Artificial dermis usually takes a few weeks to be engrafted and is generally followed by split-thickness skin grafts (STSG). The sandwich technique using artificial dermis is relatively new, in which meshed STSG is covered by the artificial dermis during the same surgery. To elucidate the clinical effects of the sandwich technique, a multicenter prospective observational study was planned and initiated. Expected favorable effects of the sandwich technique include: 1) shortening the treatment period for deep skin wounds, compared with historical artificial dermis grafting that is followed by STSG, and 2) decreasing the donor-site area for extensive skin wounds, compared with the limited ratio of meshed STSG. Considering that many cofounding factors exist when determining the surgical technique for skin grafts, the appropriate selection of covariates and optimal methods for the evaluation of outcomes were discussed prior to study initiation. The current study will hopefully generate the background knowledge necessary for a randomized controlled trial.</p>

Journal

Keywords

Details 詳細情報について

  • CRID
    1390861416263346560
  • DOI
    10.34366/jburn.49.5_263
  • ISSN
    24351571
    0285113X
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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