Development and Practical Use of Integrating Regenerative Medicine and Nanotechnology

DOI
  • TOGO Tomomi
    Pharmaceutical & Beauty Science Research Center, Material Business Division, Hosokawa Micron Corporation, JAPAN
  • TANAKA Moe
    Pharmaceutical & Beauty Science Research Center, Material Business Division, Hosokawa Micron Corporation, JAPAN
  • OCHI Ayaka
    Pharmaceutical & Beauty Science Research Center, Material Business Division, Hosokawa Micron Corporation, JAPAN
  • TAKATA Mao
    Pharmaceutical & Beauty Science Research Center, Material Business Division, Hosokawa Micron Corporation, JAPAN
  • SASAI Aiko
    Pharmaceutical & Beauty Science Research Center, Material Business Division, Hosokawa Micron Corporation, JAPAN
  • TSUJIMOTO Hiroyuki
    Material Business Division Director, Director & Operating Officer, Hosokawa Micron Corporation, JAPAN
  • MESHITSUKA Midori
    Director, M Regenerative Clinic, JAPAN
  • YAMAMOTO Hiromitsu
    Professor, School of Pharmacy, Pharmaceutical Engineering, Aichi Gakuin University, JAPAN

Bibliographic Information

Other Title
  • 再生医療とナノテクノロジーを融合した技術開発と実用化

Abstract

<p>Human Stem Cell Culture Supernatant, a product of regenerative medicine and stem cell research, contains various cell growth factors and bioactive substances. It has diverse and multifaceted mechanisms of action, so that it is capable of activating cellular functions and promoting the production of constituent components. Consequently, it has attracted attention as a groundbreaking cosmetic ingredient and is being used accordingly.</p><p>In this paper, the functionality of a smart technology that fuses human stem cell culture fluid and PLGA nanospheres was verified. The results suggest excellent collagen-producing ability, especially in the epidermis and dermis, and indicate that the technology can be expected to be utilized in aging care cosmetics. It has been demonstrated that PLGA NS work as a highly useful delivery technology, which facilitates penetration of ingredients like HSCCS, despite their large molecular size, deep into the skin, and retains them at the site of action, ensuring a long-lasting effect.</p>

Journal

  • THE MICROMERITICS

    THE MICROMERITICS 67 (0), 61-69, 2023-12-15

    Hosokawa Micron Corporation

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