Demographic Traits, Clinical Status, and Comorbidities of Patients With Thromboangiitis Obliterans in Japan
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- Watanabe Yoshiko
- Department of General Medicine, Kawasaki Medical School
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- Shimizu Yuuki
- Department of Cardiology, Nagoya University Graduate School of Medicine
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- Hashimoto Takuya
- Department of Vascular Surgery, Saitama Medical Center, Saitama Medical University
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- Iwahashi Toru
- Department of Cardiovascular Surgery, Tokyo Medical University
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- Shigematsu Kunihiro
- Department of Vascular Surgery, International University of Health and Welfare, Mita Hospital
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- Nakaoka Yoshikazu
- Department of Vascular Physiology, National Cerebral and Cardiovascular Center Research Institute
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- Harigai Masayoshi
- Division of Rheumatology, Department of Internal Medicine, Tokyo Women’s Medical University School of Medicine
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<p>Background: The latest demographics, clinical and living conditions, and comorbidities of patients with thromboangiitis obliterans (TAO) in Japan are unknown.</p><p>Methods and Results: We conducted a retrospective cross-sectional survey using the annual database of the Japanese Ministry of Health, Labour and Welfare medical support system for patients with TAO between April 2013 and March 2014. This study included 3,220 patients (87.6% male), with current age ≥60 years in 2,155 patients (66.9%), including 306 (9.5%) patients aged ≥80 years. Overall, 546 (17.0%) had undergone extremity amputation. The median interval from onset to amputation was 3 years. Compared with never smokers (n=400), 2,715 patients with a smoking history had a higher amputation rate (17.7% vs. 13.0%, P=0.02, odds ratio [OR]=1.437, 95% confidence interval [CI]=1.058–1.953). A lower proportion of workers and students was seen among patients after amputation than among amputation-free patients (37.9% vs. 53.0%, P<0.0001, OR=0.542, 95% CI=0.449–0.654). Comorbidities, including arteriosclerosis-related diseases, were found even in patients in their 20–30 s.</p><p>Conclusions: This large survey confirmed that TAO is not a life-threatening but an extremity-threatening disease that threatens patients’ professional lives. Smoking history worsens patients’ condition and extremity prognosis. Long-term total health support is required, including care of extremities and arteriosclerosis-related diseases, social life support, and smoking cessation.</p>
収録刊行物
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- Circulation Journal
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Circulation Journal 88 (3), 319-328, 2024-02-22
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390862179308795520
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL書誌ID
- 033364372
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- PubMed
- 37423757
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
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- 使用不可