Understanding the Dissolution Mechanism of Hydrophobic Dyes through Statistical Thermodynamics

DOI
  • Kanasaki Yu
    National Institute of Advanced Industrial Science and Technology

Bibliographic Information

Other Title
  • 統計熱力学で理解する疎水性色素の溶解メカニズム

Abstract

Hydrophobic dyes are used in water with solubilizers. Hydrotrope is a solubilizer of low molecular weight, weakly amphiphilic organics. and is known to promote solubilization of drugs, dyes, and pigments. One of most famous hydrotropes, urea, serves as an efficient solubilizing agent for dyes. In this study, in order to elucidate the molecularlevel mechanisms responsible for urea's effectiveness as a solubilizer, we apply a statistical thermodynamics approach rooted in the Kirkwood-Buff theory of solutions. Our findings demonstrate two key insights: (i) in contrast to the traditional notion of " water structure disruption, " the impact of urea on dye hydration has a relatively minor role in the solubilization process; (ii) the primary driving force for solubilization arises from the accumulation of urea molecules surrounding hydrophobic dye molecules.

Journal

  • Netsu Sokutei

    Netsu Sokutei 51 (1), 22-26, 2024-01-25

    The Japan Society of Calorimetry and Thermal Analysis

Keywords

Details 詳細情報について

  • CRID
    1390862268802323968
  • DOI
    10.11311/jscta.51.1_22
  • ISSN
    18841899
    03862615
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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