MASLD/MASH-related hepatocellular carcinoma in a 43-year-old morbidly obese patient

DOI Web Site 21 References
  • Kawaguchi Toshihiro
    Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine Kawaguchi Internal Medicine Clinic
  • Shimose Shigeo
    Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine
  • Kondo Reiichiro
    Department of Pathology, Kurume University School of Medicine
  • Sato Toshihiro
    Department of Surgery, Kurume University School of Medicine
  • Hisaka Toru
    Department of Surgery, Kurume University School of Medicine
  • Yano Hirohisa
    Department of Pathology, Kurume University School of Medicine
  • Kawaguchi Takumi
    Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine

Bibliographic Information

Other Title
  • MASLD/MASH関連肝硬変を背景に脂肪肝炎様肝細胞癌を発症した43歳高度肥満症の1例

Abstract

<p>We present the case of a 43-year-old male with metabolic dysfunction-associated steatotic liver disease (MASLD) who developed hepatocellular carcinoma (HCC). He was regularly followed by a primary care practitioner for morbid obesity, type 2 diabetes mellitus, and MALSD. Contrast-enhanced computed tomography and gadoxetic acid-enhanced magnetic resonance imaging revealed a mass in liver segment 5, suspected for HCC. Histopathologic examination of the tumor resected by laparoscopic-assisted partial hepatectomy led to the diagnosis of moderately differentiated steatohepatitic HCC. The noncancerous lesion was diagnosed as stage 4 metabolic dysfunction-associated steatohepatitis according to Brunt's classification. Eight months after initial admission, he underwent transcatheter arterial chemoembolization for recurrent HCC. The patient is currently considered a candidate for living-donor liver transplantation due to deteriorated liver functional reserve.</p>

Journal

  • Kanzo

    Kanzo 65 (3), 131-138, 2024-03-01

    The Japan Society of Hepatology

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