A Case of Transient Hyperlactatemia Induced by Intravenous Glycerol Administration in a Patient With Brain Trauma

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  • FUJISE Tomoya
    Department of Emergency and Intensive Care Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.
  • NIHEI Shun-ichi
    Department of Emergency and Intensive Care Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.
  • YAMASHITA Misako
    Department of Emergency and Intensive Care Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.
  • TAKAHASHI Yuta
    Department of Emergency and Intensive Care Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.
  • UCHIDA Takayuki
    Department of Emergency and Intensive Care Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.
  • OTSUJI Ken
    Department of Emergency and Intensive Care Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.
  • AIBARA Keiji
    Department of Emergency and Intensive Care Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.
  • KAMOCHI Masayuki
    Department of Emergency and Intensive Care Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.

Bibliographic Information

Other Title
  • グリセロール投与により一過性高乳酸血症を伴った外傷性脳損傷の1例

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Description

Elevated lactate levels are associated with a poor prognosis in patients with sepsis and shock. Intravenous glycerol administration is often used in Japan to treat patients with acute stroke or brain trauma, but such treatment can cause elevated lactate levels. We experienced a case of transient hyperlactatemia induced by intravenous glycerol administration in a patient with brain trauma. A 74-year-old woman underwent decompressive craniotomy because of loss of consciousness and brain edema. Glycerol was administered after the operation for management of the brain edema. Although the patient’s hemodynamics remained stable, her lactate level decreased and increased repeatedly. We recognized that the elevation in her lactate level was associated with the administration of intravenous glycerol. This case suggests that intravenous glycerol administration can induce transient hyperlactatemia.

Journal

  • Journal of UOEH

    Journal of UOEH 46 (1), 17-21, 2024-03-01

    The University of Occupational and Environmental Health, Japan

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