WJSAAC Phase I~V Study Reveals the Past and Present of Pediatric Allergy in Japan

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  • Nishima Sankei
    The Committee of the Prevalence of Allergic Diseases in Children, Society of Childhood Allergy in Western Japan

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  • WJSAAC第I～V相試験で見えてきた日本小児アレルギーの過去と今

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<p>WJSAAC (West Japan Studies of Asthma and Allergies in Childhood) uses the same method every 10 years, from the 1982 Phase I trial of 55,000 elementary school children in 11 prefectures in western Japan to the 2022 Phase V trial of 30,000 children. It has been held for 1st to 6th grade students in the same district and same elementary school. Analysis is currently underway, but the summary is that the prevalence of bronchial asthma (BA) peaked at 6.5% in Phase III, that decreased in Phase V. Among other comorbid allergic diseases, allergic rhinitis (AR) had the highest rate, followed by atopic dermatitis (AD), allergic conjunctivitis (AC), and pollinosis (P).</p><p>For the first half of a century in Japan, clinical research and research on pediatric allergies focused on BA, but energy has also started to be focused on AD, AR, AC, and food allergies (FA). It became as to be "total allergy". This background can be seen in the WJSAAC allergy epidemiology results.</p><p>The current environment in which we consider changes in symptom prevalence is undergoing major changes, and epidemiological methods, including treatment and management methods, need to be modified. However, accurate and continuous epidemiological surveys are necessary to formulate future plans for allergic diseases. This work is essential for the government and discussions at the national level are urgently needed.</p>

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