冠動脈における光干渉断層撮影による石灰化評価とCCTAによる石灰化体積の関係

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  • Relationship between Optical Coherence Tomography Calcification Score and CCTA Calcification Volume in Coronary Arteries
  • カンドウミャク ニ オケル ヒカリ カンショウ ダンソウ サツエイ ニ ヨル セッカイカ ヒョウカ ト CCTA ニ ヨル セッカイカ タイセキ ノ カンケイ

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<p>In recent years, percutaneous coronary intervention (PCI) has become established as a treatment for angina pectoris and acute coronary syndromes due to technological advances and improved devices. However, highly calcified lesions, which cause stent failures after stent implantation, are one of the major problems in PCI. Therefore, optical coherence tomography (OCT) is used to determine the thickness of calcification in the vessel wall to guide the treatment strategy for calcified lesions. Although OCT can evaluate the angle and thickness of calcification, it requires skilled reading and is only available in a limited number of centers. In this study, we focused on the amount of calcification measurable by CT coronary angiography (CCTA) and used CCTA to delineate slices of all calcified areas and measure their volumes. Similarly, we used OCT images to measure the angle of calcification and the thickness of calcium in the vessel wall in all slices where calcification was observed. In 18 patients undergoing PCI for angina pectoris, calcification volume on CCTA images was significantly positively correlated with calcification angle and thickness summation on OCT images. These results suggest that CCTA calcification volume may allow estimation of calcification severity by OCT and may serve as a noninvasive index to complement OCT calcification assessment.</p>

収録刊行物

  • 生体医工学

    生体医工学 62 (1), 31-36, 2024-03-10

    公益社団法人 日本生体医工学会

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