Machine Perfusion and normothermic regional perfusion can Improve Both Utilization and Outcomes in Liver Transplantation
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- Yuki Bekki
- Department of Surgery and Science, Kyushu University
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- Itoh Shinji
- Department of Surgery and Science, Kyushu University
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- Toshima Takeo
- Department of Surgery and Science, Kyushu University
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- Yoshiya Shohei
- Department of Surgery and Science, Kyushu University
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- Izumi Takuma
- Department of Surgery and Science, Kyushu University
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- Iseda Norifumi
- Department of Surgery and Science, Kyushu University
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- Tsutsui Yuriko
- Department of Surgery and Science, Kyushu University
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- Toshida Katsuya
- Department of Surgery and Science, Kyushu University
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- Nakayama Yuuki
- Department of Surgery and Science, Kyushu University
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- Ishikawa Takuma
- Department of Surgery and Science, Kyushu University
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- Ninomiya Miuzki
- Department of Surgery and Science, Kyushu University
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- Yoshizumi Tomoharu
- Department of Surgery and Science, Kyushu University
説明
<p>The aim of this study was to examine the influence of machine perfusion (MP) and normothermic regional perfusion (NRP) on the utilization and outcomes of liver transplantation (LT). Using US national data, 4642 donation after circulatory death (DCD) donors between 2016 and 2021 were analyzed. 4542 were with static cold storage(SCS), 79 were with MP(1.7%), and 21 were with NRP(0.5%).The utilization rates of liver in DCD with MP or NRP were significantly higher (P=0.001; 92.4% or 95.2% vs 70.4%). There were no graft failure with primary nonfunction or ischemic cholangiopathy after LT with MP or NRP. MP or NRP significantly increased the utilization rate of livers with favorable outcomes after LT. Increasing use of MP or NRP should be considered in low utilization donors to expand donor pool.</p>
収録刊行物
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- 移植
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移植 58 (Supplement), s127_1-s127_1, 2023
一般社団法人 日本移植学会
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詳細情報 詳細情報について
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- CRID
- 1390862623768411904
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- ISSN
- 21880034
- 05787947
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- 本文言語コード
- en
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- データソース種別
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- JaLC
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- 抄録ライセンスフラグ
- 使用不可