Patient With Gender Dysphoria Diagnosed With Multiple Sclerosis Following Takotsubo Cardiomyopathy and Ventricular Arrhythmia: A Case Report and Systematic Literature Review

DOI Web Site 1 Citations 22 References
  • Yamanaka Shinya
    Department of Internal Medicine, St. Luke's International Hospital, Japan
  • Nishihara Mariko
    Department of Internal Medicine, St. Luke's International Hospital, Japan
  • Kondo Madoka
    Department of Neurological Medicine, St. Luke's International Hospital, Japan
  • Miyata Kotaro
    Department of Cardiovascular Medicine, St. Luke's International Hospital, Japan
  • Dai Zhehao
    Department of Cardiovascular Medicine, St. Luke's International Hospital, Japan Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Japan
  • Kawai Fujimi
    Library, Department of Academic Resources, St. Luke's International University, Japan
  • Komiyama Nobuyuki
    Department of Cardiovascular Medicine, St. Luke's International Hospital, Japan

Abstract

<p>A 34-year-old transgender woman presented with ventricular tachycardia and was diagnosed with takotsubo cardiomyopathy. Further evaluation revealed an underlying diagnosis of multiple sclerosis (MS) with brainstem lesions that may have triggered takotsubo cardiomyopathy. In this report, we also systematically reviewed published cases of takotsubo cardiomyopathy and MS and found that basal type takotsubo cardiomyopathy was the most common, and most patients presented with brainstem involvement of MS. An awareness of these associations by physicians, along with multidisciplinary collaboration, may facilitate the early diagnosis and improve the prognosis of these patients. </p>

Journal

  • Internal Medicine

    Internal Medicine advpub (0), 2024

    The Japanese Society of Internal Medicine

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