Usefulness of Clinical Frailty Scale for Comprehensive Geriatric Assessment of Older Heart Failure Patients

  • Yuguchi Tadashi
    Department of Intensive Care Medicine, Nara Prefecture General Medical Center Department of Internal Medicine, Division of Cardiovascular Medicine, Aijinkai Takatsuki General Hospital
  • Nakajima Kenji
    Department of Internal Medicine, Division of Cardiovascular Medicine, Aijinkai Takatsuki General Hospital
  • Takaoka Hideyuki
    Department of Internal Medicine, Division of Cardiovascular Medicine, Aijinkai Takatsuki General Hospital
  • Shimokawa Toshio
    Clinical Study Support Center, Wakayama Medical University

抄録

<p>Background: Comprehensive geriatric assessment (CGA) is a multidisciplinary diagnostic process to identify the physical, psychological, and social functions of patients with frailty. The Clinical Frailty Scale (CFS) might aid in effectively identifying older patients with heart failure (HF) and frailty who would then reap maximum benefits from the CGA.</p><p>Methods and Results: A single-centre prospective cohort study that enrolled consecutive hospitalised patients (age ≥75 years) with HF was conducted. The Barthel index (BI), Mini Mental State Examination (MMSE), the Charlson comorbidity index (CCI), and the COntrolling NUTritional (CONUT) for CGA was used. Among 190 enrolled patients (mean age, 85.4 years; 47.9% male), all-cause mortality (primary endpoint) occurred in 45 patients and HF-related rehospitalization (secondary endpoint) in 59 patients within 1 year. The cumulative incidence of all-cause mortality was significantly higher in the high CFS group (low 6.3%, high 30.5%, P<0.001). However, the cumulative incidence of HF-related rehospitalization was not significantly different (low 26.3%, high 32.0%, P=0.304). The multivariable analysis revealed that the CFS group was independently associated with the risk of all-cause mortality. CFS showed a strong correlation with the BI and moderate correlation with the MMSE.</p><p>Conclusions: The CFS was associated with all-cause mortality within 1 year and was correlated with frailty domains of CGA.</p>

収録刊行物

  • Circulation Reports

    Circulation Reports 6 (4), 127-133, 2024-04-10

    一般社団法人 日本循環器学会

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