Successful Pregnancy Outcome in a Patient with Juvenile Idiopathic Arthritis in Adulthood, Amyloid A Amyloidosis, and Chronic Kidney Disease Using Tocilizumab with Strict Blood Pressure Control

  • Akira Taro
    Division of Rheumatology and Allergy, Osaka General Medical Center, Japan
  • Shimazu Yukiko
    Department of Obstetrics/Gynecology, Osaka General Medical Center, Japan
  • Hashimoto Nobuhiro
    Department of Kidney Disease and Hypertension, Osaka General Medical Center, Japan
  • Okushima Hiroki
    Department of Kidney Disease and Hypertension, Osaka General Medical Center, Japan
  • Suzuki Takehiro
    Division of Rheumatology and Allergy, Osaka General Medical Center, Japan
  • Tada Tomomi
    Division of Rheumatology and Allergy, Osaka General Medical Center, Japan
  • Ikoma Makiko
    Division of Rheumatology and Allergy, Osaka General Medical Center, Japan
  • Hosokawa Takashi
    Division of Rheumatology and Allergy, Osaka General Medical Center, Japan
  • Ueda Yoshiyasu
    Department of Kidney Disease and Hypertension, Osaka General Medical Center, Japan
  • Takemura Masahiko
    Department of Obstetrics/Gynecology, Osaka General Medical Center, Japan
  • Fujiwara Hiroshi
    Division of Rheumatology and Allergy, Osaka General Medical Center, Japan

抄録

<p>Pregnancies with chronic kidney disease (CKD) and high disease activity in rheumatic diseases are high-risk events with adverse outcomes for both the mother and fetus. We herein report a 35-year-old woman with juvenile idiopathic arthritis (JIA), amyloid A (AA) amyloidosis related to JIA, and CKD stage G4A2 who wished to have children. She achieved a successful pregnancy, even in the presence of these multiple risk factors, using tocilizumab to control the disease activity of JIA and AA amyloidosis, along with antihypertensive drugs to control her blood pressure before and during pregnancy. </p>

収録刊行物

  • Internal Medicine

    Internal Medicine 63 (9), 1311-1316, 2024-05-01

    一般社団法人 日本内科学会

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