Successful Pregnancy Outcome in a Patient with Juvenile Idiopathic Arthritis in Adulthood, Amyloid A Amyloidosis, and Chronic Kidney Disease Using Tocilizumab with Strict Blood Pressure Control
-
- Akira Taro
- Division of Rheumatology and Allergy, Osaka General Medical Center, Japan
-
- Shimazu Yukiko
- Department of Obstetrics/Gynecology, Osaka General Medical Center, Japan
-
- Hashimoto Nobuhiro
- Department of Kidney Disease and Hypertension, Osaka General Medical Center, Japan
-
- Okushima Hiroki
- Department of Kidney Disease and Hypertension, Osaka General Medical Center, Japan
-
- Suzuki Takehiro
- Division of Rheumatology and Allergy, Osaka General Medical Center, Japan
-
- Tada Tomomi
- Division of Rheumatology and Allergy, Osaka General Medical Center, Japan
-
- Ikoma Makiko
- Division of Rheumatology and Allergy, Osaka General Medical Center, Japan
-
- Hosokawa Takashi
- Division of Rheumatology and Allergy, Osaka General Medical Center, Japan
-
- Ueda Yoshiyasu
- Department of Kidney Disease and Hypertension, Osaka General Medical Center, Japan
-
- Takemura Masahiko
- Department of Obstetrics/Gynecology, Osaka General Medical Center, Japan
-
- Fujiwara Hiroshi
- Division of Rheumatology and Allergy, Osaka General Medical Center, Japan
Abstract
<p>Pregnancies with chronic kidney disease (CKD) and high disease activity in rheumatic diseases are high-risk events with adverse outcomes for both the mother and fetus. We herein report a 35-year-old woman with juvenile idiopathic arthritis (JIA), amyloid A (AA) amyloidosis related to JIA, and CKD stage G4A2 who wished to have children. She achieved a successful pregnancy, even in the presence of these multiple risk factors, using tocilizumab to control the disease activity of JIA and AA amyloidosis, along with antihypertensive drugs to control her blood pressure before and during pregnancy. </p>
Journal
-
- Internal Medicine
-
Internal Medicine 63 (9), 1311-1316, 2024-05-01
The Japanese Society of Internal Medicine