An Autopsy Case of COVID-19 with New Diffuse Pulmonary Ossification

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  • Nakagawa Taisuke
    Department of Respiratory Medicine, Graduate School of Medical Sciences, Kyushu University, Japan Department of Respiratory Medicine, National Hospital Organization Fukuokahigashi Medical Center, Japan
  • Kotetsu Yasuaki
    Department of Respiratory Medicine, Graduate School of Medical Sciences, Kyushu University, Japan
  • Takizawa Katsumi
    Department of Pathology, National Hospital Organization Fukuokahigashi Medical Center, Japan
  • Yoshimi Michihiro
    Department of Respiratory Medicine, National Hospital Organization Fukuokahigashi Medical Center, Japan
  • Okamoto Isamu
    Department of Respiratory Medicine, Graduate School of Medical Sciences, Kyushu University, Japan
  • Takata Shohei
    Department of Respiratory Medicine, National Hospital Organization Fukuokahigashi Medical Center, Japan

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Description

<p>We present the case of a 61-year-old man who developed coronavirus disease 2019 (COVID-19) and died during treatment for relapsing polychondritis. The patient was intubated and treated with steroid pulse therapy, remdecivir, antibacterial agents, baricitinib, and tocilizumab. However, his respiratory condition worsened, and he died 108 days after disease onset. An autopsy revealed diffuse alveolar damage in the fibrotic phase in all lung lobes, diffuse pulmonary ossification, and cytomegalovirus-infected cells in the middle lobe of the right lung. We herein discuss the clinical features and pathological findings of COVID-19 in immunosuppressed patients. </p>

Journal

  • Internal Medicine

    Internal Medicine 63 (10), 1459-1463, 2024-05-15

    The Japanese Society of Internal Medicine

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