The clinical features and CT scan findings associated with posttraumatic seizures

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  • 当院における急性症候性発作を伴った頭部外傷の臨床的特徴
  • トウ イン ニ オケル キュウセイ ショウコウセイ ホッサ オ トモナッタ トウブ ガイショウ ノ リンショウテキ トクチョウ

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<p>  It is clinically important to prevent posttraumatic seizures (PTSs) as they are associated with the development of posttraumatic epilepsy and other poor outcomes. To identify the characteristics of traumatic brain injury (TBI) associated with PTS, we retrospectively analyzed the cases of 56 patients who were admitted to Wakayama Medical University Hospital between January and October 2022 for a TBI, and we excluded the seven patients died within 30 days of admission. Forty‒nine patients were thus included; 11 had PTS (seizure group) and 38 had no PTS (non‒seizure group). The seizure‒group patients were significantly older than the non‒seizure group (81.2 ± 12.4 vs. 63.5 ± 26.4 years, p=0.022, S=363, Z=2.28). The initial Abbreviated Head Injury Score was significantly more severe in the seizure group (p=0.0017, S=397, Z=3.14). All of the seizure‒group patients had an acute subdural hematoma. We also observed that contusions in the primary motor cortex and temporal base‒subdural hematoma might be associated with PTS (Fisher’s exact test, p=0.028 and p=0.021, respectively). Our results suggest that older age, a severe TBI, acute subdural hematoma, TB‒SDH, and/or a contusion in the primary motor cortex might be the risk factors for PTS. A prospective study is necessary to further clarify the risk factors and the significance of the early detection of PTS.</p>

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