Influence of COVID-19 on Chemotherapy in Cancer Patient

  • Nakagawa Yukinori
    Department of Pharmacy, Organization of Occupational Health and Safety Wakayama Rosai Hospital
  • Okada Masaya
    Department of Pharmacy, Organization of Occupational Health and Safety Wakayama Rosai Hospital
  • Miyake Miyuki
    Department of Pharmacy, Organization of Occupational Health and Safety Wakayama Rosai Hospital
  • Omoto Naoko
    Department of Pharmacy, Organization of Occupational Health and Safety Wakayama Rosai Hospital
  • Hoso Naoko
    Department of Pharmacy, Organization of Occupational Health and Safety Wakayama Rosai Hospital
  • Nakatani Ryosuke
    Department of Pharmacy, Japanese Red Cross Tokushima Hospital
  • Sakaguchi Rin
    Department of Hematology, Organization of Occupational Health and Safety Wakayama Rosai Hospital
  • Shimokawa Fukuko
    Department of Pharmacy, Organization of Occupational Health and Safety Wakayama Rosai Hospital

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Other Title
  • 担がん患者における化学療法に対するCOVID-19の影響について

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<p>When a patient with cancer becomes infected with COVID-19, disease progression occurs due to the disease becoming more severe or treatment for the underlying disease being interrupted. We investigated the outcome of COVID-19 in cancer patients and the influence on the effect of chemotherapy. The subjects were 45 patients with COVID-19 among 258 cancer patients who were hospitalized and underwent chemotherapy from January 2022 to February 2023.</p> <p>The incidence rate of COVID-19 for each cancer type was 26.8% for blood cancer, 25.0% for lung cancer, and 11.0% for other cancers, with blood cancer and lung cancer significantly higher than other cancers. In addition, the median number of days required for Ct value ≥ 35 was 43.5 days in blood cancer patients, which was significantly longer than in lung cancer patients and other cancer patients. Of the 45 patients infected with COVID-19, 28 patients were infected during chemotherapy, and the median time from chemotherapy to infection with COVID-19 was 14 days. Twenty patients postponed chemotherapy, and the median number of postponed days was 20 days. Death within 30 days of infection with COVID-19 was observed in 2 cases of hematological cancer, 1 of which was due to exacerbation of the primary disease due to the postponement of chemotherapy. This study suggests that COVID-19 may affect the disease prognosis of cancer patients.</p>

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