Impact of the COVID-19 Pandemic on Door-to-Balloon Time for Primary Percutaneous Coronary Intervention ― Results From the Singapore Western STEMI Network ―
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- Chew Nicholas WS
- Department of Cardiology, National University Heart Centre, National University Health System
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- Sia Ching-Hui
- Department of Cardiology, National University Heart Centre, National University Health System Yong Loo Lin School of Medicine, National University of Singapore
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- Wee Hwee-Lin
- Saw Swee Hock School of Public Health, National University of Singapore
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- Benedict Loh Jia-Da
- Saw Swee Hock School of Public Health, National University of Singapore
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- Rastogi Saurabh
- Department of Cardiology, Ng Teng Fong General Hospital
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- Kojodjojo Pipin
- Department of Cardiology, National University Heart Centre, National University Health System Yong Loo Lin School of Medicine, National University of Singapore Department of Cardiology, Ng Teng Fong General Hospital
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- Chor Wei Ping Daniel
- Emergency Medicine Department, National University Hospital
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- Leong Benjamin Sieu-Hon
- Emergency Medicine Department, National University Hospital
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- Koh Brandon Chi-Ping
- Emergency Medicine Department, National University Hospital
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- Tam Howen
- Emergency Medicine Department, Ng Teng Fong General Hospital
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- Quek Lit-Sin
- Emergency Medicine Department, Ng Teng Fong General Hospital
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- Sia Winnie CH
- Department of Cardiology, National University Heart Centre, National University Health System
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- Saw Kalyar Win
- Department of Cardiology, National University Heart Centre, National University Health System
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- Tung Benjamin Wei-Liang
- Department of Cardiology, National University Heart Centre, National University Health System
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- Ng Zan Zhe-Yan
- Department of Cardiology, National University Heart Centre, National University Health System
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- Ambhore Anand
- Department of Cardiology, National University Heart Centre, National University Health System
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- Tay Edgar Lik-Wui
- Department of Cardiology, National University Heart Centre, National University Health System Yong Loo Lin School of Medicine, National University of Singapore
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- Chan Koo-Hui
- Department of Cardiology, National University Heart Centre, National University Health System
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- Lee Chi-Hang
- Department of Cardiology, National University Heart Centre, National University Health System Yong Loo Lin School of Medicine, National University of Singapore
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- Loh Joshua Ping-Yun
- Department of Cardiology, National University Heart Centre, National University Health System Yong Loo Lin School of Medicine, National University of Singapore
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- Low Adrian Fatt-Hoe
- Department of Cardiology, National University Heart Centre, National University Health System Yong Loo Lin School of Medicine, National University of Singapore
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- Chan Mark Yan-Yee
- Department of Cardiology, National University Heart Centre, National University Health System Yong Loo Lin School of Medicine, National University of Singapore
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- Yeo Tiong-Cheng
- Department of Cardiology, National University Heart Centre, National University Health System Yong Loo Lin School of Medicine, National University of Singapore
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- Tan Huay-Cheem
- Department of Cardiology, National University Heart Centre, National University Health System Yong Loo Lin School of Medicine, National University of Singapore
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- Loh Poay-Huan
- Department of Cardiology, National University Heart Centre, National University Health System Yong Loo Lin School of Medicine, National University of Singapore
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説明
<p>Background:Little is known about the effect of the coronavirus disease 2019 (COVID-19) pandemic and the outbreak response measures on door-to-balloon time (D2B). This study examined both D2B and clinical outcomes of patients with STEMI undergoing primary percutaneous coronary intervention (PPCI).</p><p>Methods and Results:This was a retrospective study of 303 STEMI patients who presented directly or were transferred to a tertiary hospital in Singapore for PPCI from October 2019 to March 2020. We compared the clinical outcomes of patients admitted before (BOR) and during (DOR) the COVID-19 outbreak response. The study outcomes were in-hospital death, D2B, cardiogenic shock and 30-day readmission. For direct presentations, fewer patients in the DOR group achieved D2B time <90 min compared with the BOR group (71.4% vs. 80.9%, P=0.042). This was more apparent after exclusion of non-system delay cases (DOR 81.6% vs. BOR 95.9%, P=0.006). Prevalence of both out-of-hospital cardiac arrest (9.5% vs. 1.9%, P=0.003) and acute mitral regurgitation (31.6% vs. 17.5%, P=0.006) was higher in the DOR group. Mortality was similar between groups. Multivariable regression showed that longer D2B time was an independent predictor of death (odds ratio 1.005, 95% confidence interval 1.000–1.011, P=0.029).</p><p>Conclusions:The COVID-19 pandemic and the outbreak response have had an adverse effect on PPCI service efficiency. The study reinforces the need to focus efforts on shortening D2B time, while maintaining infection control measures.</p>
収録刊行物
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- Circulation Journal
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Circulation Journal 85 (2), 139-149, 2021-01-25
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1391412881285536128
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- NII論文ID
- 130007975328
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL書誌ID
- 031256606
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- PubMed
- 33162491
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- 本文言語コード
- en
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- データソース種別
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- NDL
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