A Case of Resection of a Giant Mucinous Adenocarcinoma Derived from the Anal Gland with High Level of CA19-9 Antigen

  • Kumamoto Kensuke
    Department of Gastroenterological Surgery, Kagawa University, School of Medicine
  • Asano Eisuke
    Department of Gastroenterological Surgery, Kagawa University, School of Medicine
  • Furuichi Yumi
    Department of Gastroenterological Surgery, Kagawa University, School of Medicine
  • Kondo Akihiro
    Department of Gastroenterological Surgery, Kagawa University, School of Medicine
  • Kayama Hiroshi
    Department of Surgery, Maeda Hospital
  • Maeda Masahiko
    Department of Surgery, Maeda Hospital
  • Usuki Hisashi
    Department of Gastroenterological Surgery, Kagawa University, School of Medicine
  • Suzuki Yasuyuki
    Department of Gastroenterological Surgery, Kagawa University, School of Medicine

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Other Title
  • CA19-9異常高値を呈した巨大な肛門腺由来粘液癌の1切除例

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Abstract

<p>A 63-year-old man, who had been aware of a tumor around the anus three years earlier, complained of increasing tumor to a local clinic. The tumor protruded through the anal skin. As a result of biopsy, it was diagnosed as anal canal mucinous adenocarcinoma. The image findings revealed a multilocular cystic mass of 10 × 10 cm in diameter with calcification on the right side of the anus. The tumor invaded part of the prostate. No swelling of lateral lymph nodes or inguinal lymph nodes was observed. Laparoscopic abdominoperineal rectal resection with bilateral lateral lymph node dissection was performed and the tumor was completely resected. The histopathological findings showed anal gland-derived mucinous adenocarcinoma, and the stage diagnosis was pT4b (prostate) pN0 pM0, Stage IIIB. The tumor marker CA19-9, which was as high as 586 U/ml preoperatively, decreased to 3 U/ml one month after surgery. Currently, 2 years have passed since the operation without recurrence.</p>

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