A Case of Hemorrhagic Enteritis Caused by Calcium Polystyrene Sulfonate Associated with Cytomegalovirus Enteritis

  • MITSUI Hideo
    Department of Surgery, Tokyo Metropolitan Geriatric Medical Center
  • YOSHIMOTO Eri
    Department of Surgery, Tokyo Metropolitan Geriatric Medical Center
  • YOSHIDA Takashi
    Department of Surgery, Tokyo Metropolitan Geriatric Medical Center
  • KANAZAWA Nobuo
    Department of Surgery, Tokyo Metropolitan Geriatric Medical Center
  • KUROIWA Koujirou
    Department of Surgery, Tokyo Metropolitan Geriatric Medical Center

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Other Title
  • CMV腸炎に続発したCPSによる出血性回盲部炎の1例
  • 症例 CMV腸炎に続発したCPSによる出血性回盲部炎の1例
  • ショウレイ CMV チョウエン ニ ゾクハツ シタ CPS ニ ヨル シュッケツセイカイ モウブエン ノ 1レイ

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Abstract

<p>A 60-year-old man who was being followed for cytomegalovirus (CMV) enteritis was referred to our hospital with a chief complaint of anemia. Lower gastrointestinal endoscopy showed mucosal redness, edema, and ulceration in the ileocecal region. The results of biopsy showed no CMV antigen-positive cells, and deposition of unstructured basophilic material was observed in the lamina propria. The patient was taking calcium polystyrene sulfonate (CPS) at that time. Considering the possibility of a relapse of CMV enteritis, administration of antiviral drugs was resumed, and the CPS was discontinued. Thus, conservative treatment was started. However, his enteritis with hemorrhage did not improve, so a laparoscopic-assisted ileocecal resection was finally performed. The patient's postoperative condition was good, his anemia improved, and he was discharged on the 10th postoperative day. On histopathological examination, lesions and ulcers were seen in the ileum and cecum, and deposition of unstructured basophilic material was observed in the area from the mucosa into the muscle layer. No nuclear inclusions or CMV antigen-positive cells were found; thus, he was diagnosed with hemorrhagic enteritis caused by CPS associated with CMV enteritis.</p>

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