Mediastinal Neuroendocrine Carcinoma Slowly Growing for 8 Years after Surgical Resection of Esophageal Squamous Cell Carcinoma

  • Hirose Suguru
    Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
  • Hasegawa Naoyuki
    Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
  • Kawai Hitomi
    Department of Pathology, University of Tsukuba Hospital, Japan
  • Yamaura Masamichi
    Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
  • Mizui Tsuneo
    Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
  • Komatsu Yoshiki
    Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
  • Nagase Masaomi
    Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
  • Sato Masashi
    Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
  • Hattori Junji
    Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
  • Endo Masato
    Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
  • Yamamoto Yoshiyuki
    Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
  • Ishige Kazunori
    Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
  • Fukuda Kuniaki
    Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
  • Hyodo Ichinosuke
    Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
  • Mizokami Yuji
    Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan Endoscopic Center, University of Tsukuba Hospital, Japan

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Description

<p>A 70-year-old woman was referred to our department due to a solitary mediastinal tumor which gradually grew near the site of anastomosis for 8 years after radical surgery of esophageal squamous cell carcinoma. It was difficult to distinguish the lymph node recurrence of esophageal cancer from another tumor of unknown primary origin. Endoscopic ultrasound-guided fine-needle aspiration was performed, and the tumor was diagnosed to be neuroendocrine carcinoma. She received concurrent chemoradiotherapy with etoposide plus cisplatin. After the completion of chemoradiotherapy, the tumor disappeared. A solitary growing tumor which develops after radical resection of cancer would be better to be examined histologically in order to make an accurate diagnosis and select the most appropriate treatment. </p>

Journal

  • Internal Medicine

    Internal Medicine 59 (20), 2505-2509, 2020-10-15

    The Japanese Society of Internal Medicine

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