A simple laboratory procedure for black mycosis (<i>Exophiala</i> spp.)

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  • 黒色真菌症（<i>Exophiala</i>属）の簡易検査法と薬剤感受性試験の検討
  • 黒色真菌症(Exophiala属)の簡易検査法と薬剤感受性試験の検討
  • コクショク シンキンショウ(Exophialaゾク)ノ カンイ ケンサホウ ト ヤクザイ カンジュセイ シケン ノ ケントウ

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Abstract

<p>In recent years, the incidence of phaeohyphomycosis in immunocompromised patients with underlying diseases such as diabetes, leukemia, and hematopoietic disorders has tended to increase. The causative organisms are fungi, namely, Exophiala jeanselmei and Exophiala dermatitidis. Black fungal infections are classified into chromoblastomycosis, phaeohyphomycosis, and fungal tumors on the basis of the parasitic form in tissues. These black fungi often cannot be identified owing to insufficient knowledge and technology. In this study, we examined a simple method of identifying these Exophiala spp. and their antifungal sensitivity. As a result, we found that their identification was possible and relatively easy on the basis of their temperature tolerance and by slide culture using selective media, and by the Antifungal Susceptibility Testing of Yeast (ASTY), which could facilitate visual judgment and is useful for antifungal sensitivity examination.</p>

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