Initial experience of high-dose helical tomotherapy for medically inoperable esophageal cancer patients
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- Tate Etsuko
- Department of Radiation Oncology, Tokyo-Edogawa Cancer Center, Edogawa Hospital
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- Hama Yukihiro
- Department of Radiation Oncology, Tokyo-Edogawa Cancer Center, Edogawa Hospital
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- Hashimoto Manabu
- Department of Radiology and Radiation Oncology, Akita University Graduate School of Medicine
この論文をさがす
説明
<p>Purpose: Helical tomotherapy (HT) is one of the radiotherapy methods that has become widespread in recent years. The aim of this study is to investigate the safety of high-dose HT for medically inoperable esophageal cancer that is unable to tolerate chemoradiotherapy.</p><p>Methods: Eight patients with medically inoperable esophageal squamous cell carcinoma who cannot tolerate chemoradiotherapy were irradiated to 60 Gy at 2 Gy/fraction with HT.</p><p>Results: The 1-, and 2-year overall survival rate were 75.0%, and 46.9%, respectively. The 1-, and 2-year locoregional recurrence-free survival rate ware 72.9%, and 72.9%, respectively. Three patients developed grade 2 or 3 hematological acute toxicity, and one patient developed grade 2 late pericardial effusion.</p><p>Conclusions: Medically inoperable patients with esophageal cancer who cannot tolerate chemoradiotherapy might be treated safely by high-dose HT with minimal adverse events.</p>
収録刊行物
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- Personalized Medicine Universe
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Personalized Medicine Universe 9 (0), 15-19, 2020-10-31
一般社団法人 国際個別化医療学会
