Antibacterial and Antihemolytic Activity of Triterpenes and β-Sitosterol Isolated from Chinese Quince (Chaenomeles sinensis)

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  • カリン(Chaenomeles sinensis)果実より単離されたトリテルペン及びβ-sitosterolの抗菌活性及び抗溶血活性
  • カリン Chaenomeles sinensis カジツ ヨリ タンリサレタ
  • カリン(Chaenomeles sinensis)果実より単離されたトリテルペン及びβ-sitosterolの抗菌活性及び抗溶血活性

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An ethanolic extract of Chinese Quince (Chaenomeles sinensis KOEHNE) was found to have an antibacterial activity on Streptococcus pyogenes (group A streptococcus haemolyticus) and an antihemolytic activity on streptolysin 0 known, a pathogenic factor of S. pyogenes. Chromatographic separation of the extract gave six triterpenes and β-sitosterol, some showing a potent antibacterial activity on S. pyogenes and an antihemolytic activity. The biological activities of the compounds isolated from Chinese Quince, and authentic triterpene and sterol samples were compared, and their structure-activity relationship was investigated.


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