Effects of Several Virucidal Agents on Inactivation of Influenza, Newcastle Disease, and Avian Infectious Bronchitis Viruses in the Allantoic Fluid of Chicken Eggs
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- Abe Motoharu
- The Chemo-Sero-Therapeutic Research Institute, Japan
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- Kaneko Kumi
- The Chemo-Sero-Therapeutic Research Institute, Japan
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- Ueda Ai
- The Chemo-Sero-Therapeutic Research Institute, Japan
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- Otsuka Hiroshi
- The Chemo-Sero-Therapeutic Research Institute, Japan
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- Shiosaki Kouichi
- The Chemo-Sero-Therapeutic Research Institute, Japan
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- Nozaki Chikateru
- The Chemo-Sero-Therapeutic Research Institute, Japan
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- Goto Shuro
- The Chemo-Sero-Therapeutic Research Institute, Japan
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抄録
<p>General theories on the inactivation of viruses in the presence of a concentrated protein, such as the allantoic fluid of chicken eggs, are not useful. That is, although sodium hypochlorite and sodium hydroxide are generally known as strong virucidal agents, they do not sufficiently inactivate viruses in allantoic fluid. We found that benzalkonium chloride (BC) is an effective virucidal agent against influenza, Newcastle disease, and avian infectious bronchitis viruses even in the presence of a concentrated protein. BC is easily biodegradable by activated sludge and is not very harmful to humans. We strongly recommend BC as a useful virucidal agent, especially in the manufacture of vaccines for these viruses.</p>
収録刊行物
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- Japanese Journal of Infectious Diseases
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Japanese Journal of Infectious Diseases 60 (6), 342-346, 2007-11-28
国立感染症研究所
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詳細情報 詳細情報について
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- CRID
- 1390580461190391040
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- NII論文ID
- 40015714567
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- NII書誌ID
- AA1132885X
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- ISSN
- 18842836
- 13446304
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- NDL書誌ID
- 9273328
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可