Synthesis and photocleavage of 7-〔{Bis(carboxymethyl)amino}-coumarin-4-yl〕methyl-caged neurotransmitters

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  • Synthesis and photocleavage of 7 Bis carboxymethyl amino coumarin 4 yl methyl caged neurotransmitters

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<jats:title>Abstract</jats:title> <jats:p>7-[{Bis(carboxymethyl)amino}coumarin-4-yl]methyl-caged neurotransmitters (glutamate and GABA) were synthesized. Both caged compounds showed sufficient stability in the dark, were water-soluble at pH 7.2 without using organic solvents, and exhibited relatively high quantum yield for photolysis upon irradiation with 390 nm light.</jats:p>

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