Neurobehavior and Mental Ddvelopment of Newbom Infants Delivered under Epidural Analgesia with Bupivacaine

  • MORIKAWA,Shigetoshi
    Department of Obstetrics and Gynecology, Fujita-Gakuen Health University Banbuntane-Houtokukai Hospital
  • ISHIKAWA,Junko
    Department of Obstetrics and Gynecology, Fujita-Gakuen Health University Banbuntane-Houtokukai Hospital
  • KAMATSUKI,Hiroshi
    Department of Obstetrics and Gynecology, Fujita-Gakuen Health University Banbuntane-Houtokukai Hospital
  • SHINZATO,Yasutaka
    Department of Obstetrics and Gynecology, Fujita-Gakuen Health University Banbuntane-Houtokukai Hospital
  • WATANABE,Asaka
    Department of Obstetrics and Gynecology, Fujita-Gakuen Health University Banbuntane-Houtokukai Hospital
  • ISHIKAWA,Hiroshi
    Department of Obstetrics and Gynecology, Fujita-Gakuen Health University Banbuntane-Houtokukai Hospital
  • CHIHARA,Hiromu
    Department of Obstetrics and Gynecology, Fujita-Gakuen Health University Banbuntane-Houtokukai Hospital
  • NAGATA,Tetsurou
    Department of Obstetrics and Gynecology, Fujita-Gakuen Health University Banbuntane-Houtokukai Hospital
  • KOMETANI,Kunio
    Department of Obstetrics and Gynecology, Fujita-Gakuen Health University Banbuntane-Houtokukai Hospital

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Other Title
  • 硬膜外麻酔分娩によって生まれた児の神経行動と精神発達の検討

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Abstract

The neurobehavior of newborn infants delivered under epidural analgesia with bupivacaine was analyzed by Amiel-Tison's Neurological and Adaptive Capacity Score (NACS), while Tsumori-Inage's questionaire assessed the above infants' mental development. Seventy-two newborn infants under epidural analgesia (39 delivered spontaneously and 33 by vacuum extraction) and twenty-eight newborn infants without epidural analgesia as controls (15 delivered spontaneously and 13 by vacuum extraction) were under study. The following results were obtained 1) In the 24 hour period following childbirth, NACS tended to be low in relation to the total dosage of bupivacaine administered to the mother. 2) In the 24 hour period following childbirth and continuing until the 3rd day, NACS were relatively low regardless of the mode of delivery. 3) There was no significant difference between the neonatal physiological weight loss in newborn infants under epidural analgesia and those without epidural analgesia (controls). 4) Newborn infants under epidural analgesia displayed an average mental quotient at the first, third, and sixth month after chidbirth. Although epidural analgesia with bupivacaine might lower the neurobehavior of newborn infants in the immediate postchildbirth period, the newborn infants should return to normal without any complications.

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