A General Equation of Biological Life Span (Special Features on Degradation, Aging and Life Cycle)

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  • 生物の汎寿命モデル(<小特集>劣化・老化とライフサイクル)

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Data in the life tables were already analyzed by authors with the mixed Weibull model. The history of evolution of human life span since the pre-historical era to the present time was contemplated. Attempt of the continuing analysis is to describe the life table data with a simple generalized equation. As the first trial, so called "vital capacity" is presented as the difference between the speed of essential stem cell division and of apoplotic programmed death of the stem cell. However, the fitness of this model to the observed life table is not sufficient. In the second model, the product of the speed of stem cell division and exponential decade function was used. In addition to the new function, a logistic function, which present the hazard effect of environmental factors, i.e., limit of food, living space, or invasion of carnivores, bacteria etc., is added as a form of product. The simulation of life tables by this new general equation is fundamentally satisfactory, although it needs more precise analysis.

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