Fetal Asphyxia Diagnosed by Umbilical Arterial Blood and Subsequent Prognosis

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  • 臍帯動脈血液ガスからみたfetal asphyxiaと新生児の予後

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We assessed neonatal complications and long term prognosis in term and singleton infants born with severe metabolic acidosis (i.e., umbilical arterial blood pH<7.00 and base deficit>12mEq/L). During the study period, 3, 160 neonates were evaluated. Mean arterial blood pH was 7.298±0.079 (mean±SD), and mean base deficit was 4.5±3.2. Of the 3, 160 neonates, 14 (0.4%) were born with severe metabolic acidosis and defined as the fetal asphyxial group. Neonatal complications included (1) neonatal death, (2) resuscitation at birth with positive pressure ventilation, (3) admission to the neonatal intensive care unit for 7 days or longer, (4) mechanical ventilation, and (5) seizure. The rate of neonatal complications in the asphyxial group was higher (9/14, 64%) than that in the total population (305/3, 160, 9.7%), but no neonate in the asphyxial group had unfavorable long term prognosis. Neonates born with severe metabolic acidosis were at great risk of having neonatal complications, but their subsequent prognosis was good.

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