An investigation of childhood cancer patients with blood culture-positive experienced in our hospital

NDL Digital Collections 5 References
  • KATSUMI,Yoshiki
    Department of Pediatrics, Kyoto Prefectural University of Medicine:Department of Pediatrics, Nantan General Hospital
  • IEHARA,Tomoko
    Department of Pediatrics, Kyoto Prefectural University of Medicine
  • KIKUCHI,Ken
    Department of Pediatrics, Kyoto Prefectural University of Medicine:Department of Pediatrics, Kyoto Prefectural Yosanoumi Hospital
  • MIYACHI,Mitsuru
    Department of Pediatrics, Kyoto Prefectural University of Medicine
  • HIRASHIMA,Yoshiaki
    Department of Pediatrics, Kyoto Prefectural University of Medicine
  • NAKATANI,Takuya
    Department of Pediatrics, Kyoto Prefectural University of Medicine
  • YAGYU,Shigeki
    Department of Pediatrics, Kyoto Prefectural University of Medicine
  • TSUBAI-SHIMIZU,Satoko
    Department of Pediatrics, Kyoto Prefectural University of Medicine
  • TSUCHIYA,Kunihiko
    Department of Pediatrics, Kyoto Prefectural University of Medicine
  • IMAMURA,Toshihiko
    Department of Pediatrics, Kyoto Prefectural University of Medicine
  • MORIMOTO,Akira
    Department of Pediatrics, Kyoto Prefectural University of Medicine
  • FUJITA,Naohisa
    Department of Infection control, Kyoto Prefectural University of Medicine:Department of Clinical Laboratory, Kyoto Prefectural University of Medicine
  • HOSOI,Hajime
    Department of Pediatrics, Kyoto Prefectural University of Medicine

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Other Title
  • 当院で経験した血液培養陽性の小児がん患者からの考察

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Abstract

Purpose The purpose of this study is to investigate how to use appropriately anti-bacterial agents for childhood cancer patients in our hospital. Method This study consists of blood culture samples obtained from 56 children with cancer, who were treated from April 2005 to March 2007 in our hospital. The number of patients whose blood culture turned out positive was 18 (28 cases). Results Gram-positive cocci were detected in 19 cases (67.9%) of positive blood culture samples. Viridans streptococci were isolated from 4 patients, who were young children suffering from a severe strain of the disease. In susceptibility tests, gram-negative rods were sensitive to broad-spectrum cephalosporin as well as to carbapenem. Staphylococci, one of the gram-positive cocci, were susceptible to minocycline as well as to glycopeptide. As for the 4 cases where viridans streptococci was detected, they eventually all needed treatment with glycopeptide. Conclusion Treatment with broad-spectrum cephalosporin is enough for treating patients with gram-negative rods-positive in our hospital. Treatment with glycopeptide for severe infection or minocycline for minor infection should be chosen according to the patient's age, symptoms and clinical course, if bacteremia caused by gram-positive cocci is suspected.

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