Catamnestic Observation of Patients with Arteriosclerosis Obliterans after Double Filtration Plasmapheresis

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  • 二重膜濾過血漿交換法による閉塞性動脈硬化症患者治療予後の検討(<特集>腎・血液領域の注目すべき疾患-アフェレシス療法のエビデンスとガイドライン-)

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Abstract

We performed both DFPP and HD in eight cases of non-hyperlipidemic patients suffering from severe arteriosclerosis obliterans in which drug treatment had been ineffective and surgical treatment was not feasible. We also conducted catamnestic observation for a period of two years. Amputation of the leg was avoided in six of seven cases, and effects of treatment remained with regard to subjective symptoms such as coldness, numbness, and pain as indicated by the Visual Analogue Scale. The current research presents DFPP as a new option for the treatment of non-hyperlipidemic patients with difficult-to-treat ASO.

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