Crystallographic Properties and Cell Affinity Study of Synthetic α-Tricalcium Phosphate, β-Tricalcium Phosphate, Tetracalcium Phosphate and Fluorapatite :

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  • Sakae,Toshiro
    Department of Anatomy, Nihon University School of Dentistry at Matsudo
  • Mishima,Hiroyuki
    Department of Anatomy, Nihon University School of Dentistry at Matsudo
  • Kozawa,Yukishige
    Department of Anatomy, Nihon University School of Dentistry at Matsudo
  • Nishimoto,Norihiko
    Department of Oral Pathology, Faculty of Dentistry, Okayama University
  • Akagi,Takumi
    Department of Oral Pathology, Faculty of Dentistry, Okayama University
  • Inoue,Masahisa
    Department of Oral Pathology, Faculty of Dentistry, Okayama University
  • Wakana,Yutaka
    Research and Development Unit, Taihei Chemical Industrial Co. Ltd.
  • Matsuda,Nobuyuki
    Research and Development Unit, Taihei Chemical Industrial Co. Ltd.
  • Nagai,Noriyuki
    Department of Oral Pathology, Faculty of Dentistry, Okayama University

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The chemical, crystallographic and cell proliferating properties of synthetic calcium phosphates were assessed. The materials used were synthesized α-tricalcium phosphate, α-Ca^4 (PO^4)^2 O, and fluorapatite, Ca-10 (PO^4)^6 (OH, F)^2. Chemical analysis and x-ray diffraction analysis confimed that these materials possessed their respective crystal structure. Cell proliferation studies showed that these synthetic calcium phosphates do not inhibit cell proliferation. These findings suggest that these materials may be used as biomaterials for a variety of purposes.

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