正常マウスの体重および体脂肪量に対する防風通聖散の作用

書誌事項

タイトル別名
  • Effects of Bofu-tsusho-san (Fang-Feng-Tong-Sheng-San) on body weight and fat content in normal mice
公開日
2001-02-28
公開者
和漢医薬学会

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説明

The effects of Bofu-tsusho-san (BOF) on body weight and fat content were investigated in normal male and female ddY mice. Mice were fed ad libitum the experimental diet containing 1.5% or 4.5% (w/w) of BOF extract for 4 weeks. In both male and female mice, BOF suppressed the body weight gain and fat accumulation without affecting food intake. BOF also reduced triglyceride content in the liver, and increased mitochondrial cytochrome c oxidase activity, a functional index of thermogenesis, in the brown adipose tissue. These results suggest that BOF has a preventive effect against body fat accumulation by inhibiting triglyceride synthesis in the liver and by enhancing the thermogenesis in the brown adipose tissue.

収集根拠 : NII-ELS
資料形態 : テキストデータ
コレクション : 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > 学術機関 > 学協会
著者所属: カネボウ株式会社漢方ヘルスケア研究所
Affiliation: Kampo & Healthcare Research Laboratories, Kanebo, Ltd.

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