Loss of ε-Aminocaproate Metabolism in Corynebacterium aurantiacum

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公開日
1982-10-25
公開者
Society of Fermentation Technology, Japan

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説明

Corynebacterium aurantiacum B-2 is characterized by its ability to grow on ε-caprolactam and cyclic oligomers of ε-aminocaproic acid (ACA) larger than the trimer as the sole source of carbon and nitrogen. Slow growth of B-2 colonies on an ACA cyclic tetramer agar medium kept in a cold room (12±3℃) for 5 weeks resulted in production, with a 32% frequency, of cells of a metabolic variant which could not grow on the cyclic tetramer, ε-caprolactam or ACA. This variant strain retained hydrolysis activities toward the cyclic tetramer, the linear dimer and ε-caprolactam, but lost the ACA transaminase activity. This high rate of curing of the ACA metabolism and the lack of reversion to the original characteristics suggest that the gene for ACA transaminase may be carried by a plasmid.

収集根拠 : NII-ELS
資料形態 : テキストデータ
コレクション : 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > 学術機関 > 学協会
著者所属: Department of Biology, Faculty of Science, Osaka City University
著者所属: (Present address)Division of Biology, Research Institute for Atomic Energy, Osaka City University

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