劇症肝不全に対する肝移植前後の肝補助の現状(<特集>劇症肝炎の治療をめぐって)

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  • The Role of Apheresis in Liver Transplantation for Fulminant Liver Failure

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Liver transplantation is a fundamental treatment for patients with end-stage hepatic failure. A living-donor liver transplantation program was started in Japan in 1989, and is still the major form of liver transplantation because of the scarcity of a cadaveric donor pool. We have performed over 900 cases of living-donor liver transplantation as of June 2003. In order to perform living-donor liver transplantations under safer conditions, apheresis plays a major role in Japan due to the prevalence of living-donor liver transplantation wherein later retransplantation is difficult. Apheresis is the main chinical indication used before transplantation and for liver support after transplantation. We describe the role of apheresis therapy in liver transplantation for fulminant liver failure.

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