Significance of the Glucose Concentration in Amniotic Fluid for the Prediction of Chorioamnionitis in Preterm Labor

HASEGAWA,Isao, MURAKAWA,Haruo, UTSUMI,Tohru, IMAI,Tsutomu, TANAKA,Kohei, FUJIMORI,Ryoju

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Other Title

切迫早産における絨毛羊膜炎の診断のための羊水中グルコース濃度測定の意義

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For the rapid and accurate prediction of the presence of chorioamnionitis (CAM) in preterm labor, amniotic fluid analyses were performed in 46 women with preterm labor between 24 to 34 weeks' pregnancy. Ultrasound-guided transabdominal amniocenthesis was performed on admission and the amniotic fluid was subjected to the measurement of cell count, glucose, protein and chlorine concentration according to cerebrospinal fluid and neutrophil esterase analysis. The data demonstrated that the amniotic fluid glucose concentration was significantly lower in women with preterm birth/CAM (+) than that with preterm birth/CAM (-) and term birth (19.0±9.1, 28.0±7.6, 51.6±14.5 mg/dl, respectively). All of the women with a glucose concentration of 20 mg/dl or less showed signs of CAM. By setting up a cut off value of 25 mg/dl, both high sensitivity (81.8%) and specificity (91.4%) for the prediction of CAM were obtained. Positive predictive values for CAM of a glucose concentration of 20 mg/dl or less and 25 mg/dl or less were 100% and 75% respectively. It was concluded that amniotic fluid glucose concentration measurement is useful for the prediction of CAM. The presence of CAM should be considered when the amniotic fluid glucose concentration is 25 mg/dl or less.

Journal

日本産科婦人科學會雜誌

日本産科婦人科學會雜誌 46 (3), 235-239, 1994-03-01

日本産科婦人科学会

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CRID: 1543950420056167552

NII Article ID: 110002108935

NII Book ID: AN00190060

Web Site: http://dl.ndl.go.jp/info:ndljp/pid/10697132; https://search.jamas.or.jp/link/ui/1994214143