- 【Updated on May 12, 2025】 Integration of CiNii Dissertations and CiNii Books into CiNii Research
- Trial version of CiNii Research Automatic Translation feature is available on CiNii Labs
- Suspension and deletion of data provided by Nikkei BP
- Regarding the recording of “Research Data” and “Evidence Data”
Pre-operative High-dose chemotherapy for infantile hepatoblastoma (PRETEXT IV)-review of our two cases
-
- MUTO,Mitsuru
- Department of Surgery, Tokyo Metropolitan Kiyose Children's Hospital
-
- HIROBE,Seiichi
- Department of Surgery, Tokyo Metropolitan Kiyose Children's Hospital
-
- TOMA,Miki
- Department of Surgery, Tokyo Metropolitan Kiyose Children's Hospital
-
- KOMORI,Koji
- Department of Surgery, Tokyo Metropolitan Kiyose Children's Hospital
-
- OKUMURA,Kenji
- Department of Surgery, Tokyo Metropolitan Kiyose Children's Hospital
-
- KANEKO,Takashi
- Department of Hematology and Oncology, Tokyo Metropolitan Kiyose Children's Hospital
-
- YONEYAMA,Hiroshi
- Department of Hematology and Oncology, Tokyo Metropolitan Kiyose Children's Hospital
-
- SUGITA,Mayumi
- Department of Hematology and Oncology, Tokyo Metropolitan Kiyose Children's Hospital
-
- HUKUOKA,Kohei
- Department of Hematology and Oncology, Tokyo Metropolitan Kiyose Children's Hospital
-
- MORIKAWA,Masahiko
- Department of Pathology, Tokyo Metropolitan Kiyose Children's Hospital
-
- KAMAGATA,Syoichiro
- Department of Surgery, Tokyo Metropolitan Kiyose Children's Hospital
-
- HAYASHI,Akira
- Department of Surgery, Tokyo Metropolitan Kiyose Children's Hospital
Bibliographic Information
- Other Title
-
- 術前超大量化学療法を行ったPRETEXT IV乳児肝芽腫2症例の検討
Search this article
Description
We report on two cases of infantile hepatoblastoma specified as PRETEXT (Pre-Treatment Extent of Disease) IV. Regimen CITA and ITEC prescribed by the JPLT-2 (Japanese Study Group for Pediatric Liver Tumor) protocol were invalid in both cases. Then, the extensive high-dose chemotherapy followed by an autologous bone marrow transplant were tried. Consequently, regimen Hi-MEC (Melpharan+Etoposide+Carboplatin) showed a poor response. On the other hand, regimen Hi-MT (Melpharan+thio-TEPA) had a great effect and the tumor could be excised completely. This is the first report about "preoperative high-dose chemotherapy" based on the JPLT-2 protocol. Hi-MT was thought to be a suitable treatment when standard chemotherapy was not effective. The treatment strategy for unresectable infantile hepatoblastoma was considered based on our experience.
Journal
-
- 小児がん : 小児悪性腫瘍研究会記録
-
小児がん : 小児悪性腫瘍研究会記録 45 (2), 158-161, 2008-05-25
がんの子供を守る会
- Tweet
Keywords
Details 詳細情報について
-
- CRID
- 1544231895055111808
-
- NII Article ID
- 110007170695
-
- NII Book ID
- AN00116159
-
- Text Lang
- ja
-
- Data Source
-
- NDL Digital Collections (NII-ELS)
- CiNii Articles
