Importance of MRI Lung to Liver Signal Ratio as a Prognosticator for Congenital Diaphragmatic Hernia

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Other Title
  • 先天性横隔膜ヘルニアにおける予後予測因子としてのMRI肺-肝信号比の有用性

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Objective: Congenital diaphragmatic hernia (CDH) is a developmental defect of the diaphragm with herniation of abdominal viscera into the thorax. Factors such as ultrasound Lung to Thorax ratio (L-T ratio) have been reported as prognosticators for congenital diaphragmatic hernia. The present study investigated the usefulness of each factor as a prognosticator. Methods: Over a 7.5-year period from 1998, 13 fetuses diagnosed with congenital diaphragmatic hernia at another hospital underwent thorough testing and were delivered at our hospital; they then underwent surgery in the pediatric surgery department of our hospital. The following prognostic factors were analyzed: gestational age at detection, ultrasound L-T ratio, MRI lung to liver ratio, hepatic protrusion into the thoracic cavity and gender. Results: Ten patients are alive, while three patients died after birth. Survival rates and p-values for each factor were as follows. 1) gestational age at detection: before gestational week 24, 3/3 (100%), after gestational week 25, 6/10 (60%), p=0.37. 2) L to Tratio: 0.2≦, 5/6 (83%), <0.2, 3/6 (50%), p=0.37. 3) MRI lung to liver ratio: 2.0≦, 8/8 (100%), <0.2, 1/5 (10%), p<0.005. 4) hepatic protrusion into the thoracic cavity: 4/7 (57%), no hepatic protrusion, 6/7 (85%), p=0.37. 5) gender: male, 3/6 (50%), and female, 6/7 (86%), p=0.16. Significant differences existed only for MRI lung to liver ratio. Conclusions: These results suggest that MRI lung to liver ratio represents the most useful prognosticator for congenital diaphragmatic hernia.

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Details 詳細情報について

  • CRID
    1570009752380857344
  • NII Article ID
    110006198489
  • NII Book ID
    AN00043827
  • ISSN
    03855759
  • Text Lang
    ja
  • Data Source
    • CiNii Articles

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