A Case Report of Granular Cell Tumor of Peripheral Lung Origin

4 Citations
  • Yokoi Kohhei
    Pathology Division, National Cancer Center Research Institute, and Department of Surgery, National Cancer Center Hospital, Tokyo, Japan
  • Kodama Tetsuro
    Pathology Division, National Cancer Center Research Institute, Tokyo, Japan
  • Tsuburaya Masaru
    Pathology Division, National Cancer Center Research Institute, Tokyo, Japan
  • Shimosato Yuhio
    Pathology Division, National Cancer Center Research Institute, Tokyo, Japan
  • Yoneyama Takeshi
    Department of Surgery, National Cancer Center Hospital, Tokyo, Japan

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  • 左肺上葉抹消に発生したGranular Cell Tumorの1例

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A case of granular cell tumor which originated in the periphery of the left upper lobe of the lung was reported . The patient was a 48 year-old female, who was found to have an abnormal mass density in the left lung field on chest X-ray films several years previously. Left upper lobectomy was performed. The tumor was 3 cm in diameter and firm. Histologjcally tumor cells had cyioplasmic acidophilic granules which were PAS-positive after diastase digestion and strongly positive for acid phosphatase activity, Ultrastructurally tumor cells also had a large number of the pleomorphic lysosomal granules. Immunohistochemically, tumor cells showed positive reaction with anti-S-100 protein antibody. Angulate bodies were found in the stromal cells histologically and ultrastructurally. This is the second reported case of granular cell tumor of peripheral lung origin.

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