Auditory brainstem response (ABR) with the epidual recording in mice

4 References
  • TAKAHASHI Junko
    Department of Veterinary Physiology, Nippon Veterinary and Animal Science University
  • TAKASU Masaki
    Department of Veterinary Physiology, Nippon Veterinary and Animal Science University
  • SAITO Kenichi
    Department of Veterinary Physiology, Nippon Veterinary and Animal Science University
  • SUZUKI Hiroetu
    Department of Veterinary Physiology, Nippon Veterinary and Animal Science University
  • SUZUKI Katsushi
    Department of Veterinary Physiology, Nippon Veterinary and Animal Science University

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  • マウスの脳硬膜上からの聴覚脳幹誘発電位

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Mouse and rat strains of epilepsy model have been kept in our laboratory. Using these animals, the method of EEG recording has been developed and the analysis have been conducted. There are many certainties on the cause of the epileptic attack. It has been observed that squeak of animals which exhibit ictal symptoms seem to cause the attack in other animals and that the epilepsy was caused by tossing up maneuvers. As the first step to clarify the relation between epilepsy and auditory response, we recorded the auditory brainstem response (ABR) in mice. In the present experiment, we recorded EEG from 4 monopolar electrodes placed on the dura mater through burr holes of the skull of epilepsy prone El mice and its mother strain ddY mice. 1024 EEG recording for 10msec after click sound stimulation were summed up to obtain ABR, the resulted ABR was highly reproducible in terms of latency and amplitude of ABR peaks, although there was a strain difference in the pattern of ABR.

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