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Enzymes and Catalysts. II. : Pig Liver Esterase-Catalyzed Asymmetric Synthesis of (-)- and (+)-Cucurbitine and Its (-)-Thio Analogue(Organic,Chemical)
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- MORIMOTO YOSHIHISA
- Shizuoka College of Pharmacy
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- ACHIWA KAZUO
- Shizuoka College of Pharmacy
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Description
The asymmetric synthesis of (-)- and (+)-cucurbitine was carried out by a method involving 1,3-dipolar cycloaddition of the intermediary azomethine ylide and pig liver esterase (PLE)-catalyzed hydrolysis. The thio analogue, (-)-3-aminotetrahydrothiophene-3-carboxylic acid, was also synthesized.
Journal
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- Chemical & pharmaceutical bulletin
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Chemical & pharmaceutical bulletin 35 (9), 3845-3849, 1987-09-25
The Pharmaceutical Society of Japan
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Keywords
Details 詳細情報について
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- CRID
- 1570291227372146944
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- NII Article ID
- 110006281510
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- NII Book ID
- AA00602100
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- ISSN
- 00092363
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- Text Lang
- en
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- Data Source
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- CiNii Articles